Quid Cellulose aether est late in pharmaceutical excipients?

Pharmaceutical excipients sunt excipients et adjuncts in productione et dispensationem medicinae, et sunt magni momenti pars pharmaceutical apparatu. Cellulose ether as derived from natural polymer material, has the characteristics of biodegradable, nontoxic, cheap, such as sodium carboxymethyl cellulose, methyl cellulose, hydroxypropyl methyl cellulose, hydroxypropyl cellulose, ethyl cellulose and hydroxyethyl cellulose, cellulose ether has important application value in the pharmaceutical excipients. In praesenti, maxime ex products de domesticis Cellulose aether conatibus sunt maxime applicari ad humilis-finem industria, quod additum valorem non altum, in industria est in urgente necessitate et non alta, industria est in urgente necessitate et upgrading, amplio in altum finem application of products.

Pharmaceutical excipients foro potentiale est ingens

PHARMACEUTICAL excipients ludere an maximus munus in progressionem et productionem of pharmaceutical praeparatio. For example, in sustained-release preparations, cellulose ether and other polymer materials as pharmaceutical excipients have been widely used in sustained-release pellets, various framework sustained-release preparations, coating sustained-release preparations, sustained-release capsules, sustained-release film, resin drug sustained-release preparations and liquid sustained-release preparations. In hac ratio, cellulosa aether et alias polymers sunt plerumque usus est ut carrier medicinae ad control release rate of pharmaca in humano corpore, id est, requiritur ad quodam tempore range ad consequi ad causam in aliquam tempus range ad consequi ad causam in aliqua tempus range ad consequi ad causam in aliqua tempus range ad consequi ad causam in aliquo tempore range ad consequi ad causam in aliquam tempus range ad consequi ad causam in aliqua tende ad consequi ad causam in aliqua tende ad consequi ad causam in aliqua parte ad consequi ad causam in aliqua tende ad consequi ad causam in aliqua parte ad consequi ad causam in aliqua tente ad consequi ad causam ad consequi ad causam in aliqua tente ad consequi ad causam in aliqua parte ad consequi ad causam in aliqua treatore ad consequi ad causam in aliqua parte ad consequi ad consequi ad causam in aliquam tempus range ad consequi ad causam ad causam in aliquo tempore range ad consequi ad causam in aliqua tente ad consequi ad causam ad causam in tempore ad consequi, ut ad consequi curatio in corpore ad consequi ad causam.

Secundum ad Statistics of Zhiyan Consulting et Research Department, Sina est enumerantur de D genera excipients, sed comparari cum Civitatibus Foederatis Americae (plus quam MD species), quod est magnus gap, quod genus est adhuc minus, in pharmaceutical foro progressionem potentiale est ingens. Non intellexerunt quod summo decem pharmaceutical excipients in Sina foro sunt pharmaceutical GELATINA capsule, sucrose, amulum, film coating pulveris, I, II-propylene cellulosa, HPMC, Hydroxypropyl, II-propylene Cellulose (Hydroxypropyl, HPC, Hydose.

SixPRAECIPIOCellulose aetherinpharmaceutical excipients

Naturalis Cellulose aether est alkali Cellulose et etheringing agente sub certa conditionibus reactionem ad generare seriem cellulosis derivationes, est a cellulosa Macromolucule hydroxyl aether est pars vel omnino reponi per productum. Cellulose aether est late in PETROLEUM, aedificium materiae, coatings, cibum, medicina et cotidie chemicals et alia agri, in omnibus agris, pharmaceutical products sunt basically in altum finem agro industria, cum altum est in altum agro industria, cum altum est in agro in industria, cum princeps additae valorem. Ob stricte qualitas requisita, productio of pharmaceutical gradus Cellulose aether est etiam difficilius, potest esse dicitur quod qualis est pharmaceutical gradu products potest repraesentare technica viribus cellulosa aethere. Cellulose aether est solebat ut a blocker, ossa et viscosifier addere, factum ex sustinuit-release Ossa Tablet, stomachum solutum coating materia, sustinuit-release Medicamento film agente materiae.

Sodium carboxymethyl Cellulose

Sodium carboxymethyl Cellulose (CMC-NA) est maxima cede et dosis Cellulose aether varietates domi et foris, quod factum ex bombacio, lignum alkali ex Ionicaceacetic etherono et cetera ex Ionico cellulosa aether. CMC-Na est quaedam communiter pharmaceutical excipients, communiter ut adhesives pro solidum apparatu et viscosis, crasso et suspensionem AIDS ad liquidum praeparat, tum aqua-solutum matrice et film formatam materiae. In tardus (imperium) release apparatu, quod est saepe usus est ut film agente materia ad tardus release medicinae et compage tabulas ad tardus release.

In addition to sodium carboxymethyl cellulosose ut pharmaceutical excipients, crosslined sodium carboxymethyl Cellulose potest etiam esse ut pharmaceutical excipients. Crosslinked sodium carboxymethyl cellulosose (CCMC-NA) est purificatus aqua insolubilis substantia carboxymethyl celluloste portavit cum crosslinking agente ad quaedam temperatus acidum (LXXX ℃) sub actione in acidum Catalyst. Et Crosslinking agente potest propylene Glycol, succinic anhydride, maleic anhydride et adipica anhydride. Crosslinked sodium carboxymethyl Cellulose adhibetur ut disinttring agente de tabulis, capsules et granulis in oris apparatu, freti capillaribus et tumor ad effectum est disintegrating, eius bonum compressibility, fortis disintegrating vi. Studiis ostensum est quod tumor gradus crosslined sodium carboxymethyl cellulosa in aquis maius quam humilitatem substitutis sodium carboxymethyl cellulosis et hydrated microcrystalline cellulosa et alia communis disintraging agentibus.

Methyl Cellulose

Methyl Cellulose (MC) est unum nonionic cellulosa aether ex bombacio et lignum alkalization, chlorometrhane etheronification et aliis processibus. Methyl Cellulose habet optimum aqua solubility et firmum in phantibus de 2.0 ~ 13.0. Est late in pharmaceutical excipients, sublingual tabulas, intramuscular injections, ophthalmic apparatum, oralis capsules, oris suspensionis, oris tabulis et loci apparatu. Praeterea, MC potest adhiberi ut hydrophilic gel compage sustineri, release praeparatio, CARDIACUS solutum coating materiam, sustinetur, release microcapsule coating materiam, etc.

Hydroxypropyl methyl Cellulose

Hydroxypropyl methyl Cellulose (HPMC) est a nonionic Cellulose mixto aether ex bombacio et lignum per alcalization, propylene cadmiae et chlorometrhane etherification. Est odorless, insipidum et non-toxicus, solutum in frigore aqua et gelatinosis aqua calida. Hydroxypropyl methyl cellulosis est domesticis cede, dosis et qualis est cellulosis mixto aether varietates in praeteritum XV annis cursim emendare, quod etiam unum maximae moles medicinales excipients ad domi et foris, ut medicinales excipient habet in domum suam et foris, ut est a medicinalibus excipient habet, sicut L annis, ut est de medicinalibus excipient est in domum suam et foris, ut est de medicinalibus excipient est in domum suam et foris, ut est a medicinalibus excipient est fere L annis de historia. In praesens, HPMC applicationem maxime reflectitur in sequentibus quinque facies:

Una est in ligans et disintegrating agente. HPMC ut ligans potest facere medicamento facile ad infectum, et suum aquam potest expand centum temporum, ita potest significantly amplio et dissolution vel dimittere tabulas. HPMC habet fortis Viscositas, pro texta de rigidas et fragile dura rudis materiae potest augendae eius particula viscositas, amplio eius compressibility. HPMC Low Viscosity potest esse in ligans et disintegrating agente, princeps viscositas tantum ut a ligans.

Secundum est quod tardus et imperium release materia oris apparatu. HPMC est Hydrogel compage materiam communiter in hosteined, remissionis apparatu. HPMC cum humilis Viscosity Level (V ~ 50MPA · s) potest esse ut tenaces, tenaces-enhancing agente et suspensionem auxilium, cum HPMC cum altum viscosity sustineri, et Hydrophilic Gel, sustinuit-release Tabulae. HPMC can be dissolved in gastric enteric fluid, has the advantages of good pressability, good fluidity, strong drug loading ability and drug release characteristics are not affected by pH, etc., is a very important hydrophilic carrier material in sustained release preparation system, commonly used as hydrophilic gel framework and coating material of sustained release preparation, and used in gastric floating preparation, sustained release drug film agent excipients.

Tertio, ut coating film - agente formans. HPMC has good film forming, it forms the film uniform, transparent, tough, production is not easy to stick, especially for easy moisture absorption, unstable drugs, with it as isolation layer can greatly improve the stability of drugs, prevent film discoloration. HPMC habet varietate viscosity cubitations, ut propriis lectio, coating film qualis, specie melius quam alia materiae, et communiter solebat concentration II% ~ X%.

Quartum quod capsulam capsulam materiale. In annis, cum crebris tumultu animalis epidemiam worldwide, comparari GELATINA Capsulae, Plant Capsulae facti sunt novi delicias de pharmaceutical et cibum industria. Pfizer feliciter extrahitur HPMC ex naturalibus plantis et paratus vcaptm plant capsulae. Comparari cum traditional gelatinam cavae capsules, plant Capsulae habere commoda late adaptability, nullum crucem-vinculum reactionem periculo et summus stabilitate. Release rate est relative stabilis, in singulos differentias sunt parva, et non sunt absorbetur post disintegratum in humano corpore, et ex corpore solutus est. Termini repono conditionibus per multitudinem experimentis, capsules fere non fragile sub humiditas conditionibus et proprietatibus capsules usque stabilis sub alto condiciones, et in herba capsulae non affectus in extrema condiciones et in extrema condiciones. Cum populus est intellectus plantarum capsulis, tum mutationem publica pharmacum conceptum domi et foris, in foro demanda de plant Capsulae et crescere cursim.

Quinque est sicut suspensio agente. Suspensus liquor apparatu sunt communiter in orci dosis formae, quae sunt heterogenea dispersionem systems de insolubilis solidum medicinae in liquido dispersion instrumentis. Stabilitatem systematis determinat quale suspensus liquor praeparatio. HPMC colloidal solutio potest reducere solidum-liquidum interface tensio, reducere superficiem liberum industria solidum particulas, ut heterogenea dispersionem ratio tendit ut sit stabilis, est optimum suspensionem agente. HPMC adhibetur sicut Thickener de oculo guttae et contentus est 0.45% ~ 1.0%.

Hydroxypropyl Cellulose

Hydroxypropyl Cellulose (HPC) est unum nonionic cellulosa aether ex bombacio et ligna per alcalization, propylene cadmiae etheronification et aliis processibus. HPC solere solutum aqua infra XL ℃ et numerus solitarius solvents. Et proprietates sunt ad contentus de hydroxypropyl et gradu polymerization. HPC potest esse compatible cum variis medicinae et bonum inertiae.

Low substituted hydroxypropyl cellulose (L – HPC) mainly for tablet disintegrants and adhesive, its features are: easy to suppress forming, strong applicability, especially not easy molding, plasticity and brittleness of film, joined the L – HPC can increase the hardness of tablet and the appearance of brightness, still can make tablet disintegrated rapidly, promote the intrinsic quality of the film, and meliorem curativum effectus.

Hydroxypropyl cellulosis altitudinem substitutis (h-HPC) potest esse in ligans in tabula, granula et denique granulum in pharmaceutical agri. H-HPC habet optimum amet formatam proprietas, in amet adeptus est lenta et elastica, et potest comparari plasticizer. Mixing cum aliis anti-humorem coating agentia, in film perficientur potest esse amplius melius, et communiter usus est in film coating materia in tabulis. H-HPC potest etiam esse sicut compage materiam ad parare Framework sustinetur, release tabulae, hoste-release pellets et duplex-layer sustinuit-release tabulae.

Hydroxyethyl Cellulose

Hydroxyethyl Cellulose (HEC) est unum nonionic Cellulose aether ex bombacio et ligna alkalization, ethylene cadmiae etherification et alia processibus. HEC est maxime usus est ut Thickener, Colloidal Protective agente, tenaces, dispersant, stabililerit, suspensionem agente, film formandi agente et sustinuit, release materia in medicinae agro. Non potest esse in loci medicamento emulsis, unguenta, oculus guttae, oralis liquida, solidum tabulas, capsulae et aliis dosis formae. Hydroxyethyl Cellulose est inclusa in Civitatibus Foederatis Americae Pharmacopoeia / United States National Formulary et Europae pharmacopoeia.

Ethyl Cellulose

Ethyl Cellulose (EC) est unum de maxime late usus aqua-insolubilis Cellulose derivationes. EC est non-toxicus et firmum, insolubilis in aqua, acidum aut alkali solutions, solutum in Ethanol et methanolum et alia organicum solvents. Communis solvents sunt toluene / Ethanol mixturis ex 4/1 per pondus. Eco habet plures usus in medicamento imperium, release formula, late usus est in tabellarius et imperium, release formula et microform parare materiae, usus est, ut, potest esse sicut in tabulis blosed, uti ut mixta est ut in tabella, usus est ut mixturis, tardus solebat, solebat, ut stipe solebat, ut stipare Micro pill, usus est ut stipare microform Materials praeparatio tardus release Micro capsule; Potest etiam ut late usus est in carrier materia parare solidum dispersionem. Hoc est late in pharmaceutical technology ut a amet formatam substantiam et tutela coating, tum ut ligans et filler. Sicut tutela coating tabulas, potest reducere sensitivity tabulae ad humiditatem et ne medicamentorum a affectus humida et color. Potest etiam formare tardius, release tenaces iacuit et encapsulate polymer cum microcapsules, ut medicamento effectus potest dimisit continue.

Nos mos adepto rid de mid - et humilis-finem applications et accelerare transformatio et upgrading

To sum up, the water-soluble sodium carboxymethyl cellulose, methyl cellulose, hydroxypropyl methyl cellulose, hydroxypropyl cellulose, hydroxyethyl cellulose and oil soluble ethyl cellulose with their respective features, as a binder, disintegrating agent, oral preparations slow controlled release materials, coating film formers, capsule capsule material Et suspensus auxilium in pharmaceutical excipients. Vultus in mundo, aliquot aliena multinational turmas (Iaponia Shin, etsu, Civitatibus Foederatis Americae Dow Lupus et Ashland) Ingenti in Future, aut auget productio, aut merger, aut augmentum in hoc agro. Dow nuntiatum quod erit step usque ad focus in formulationibus, ingredientia et indiget de Chinese pharmaceutical foro, tum sua conatus ad adducere applicari research propius ad forum. Dow est scriptor Cellulose division et Colfcon constituerunt a global societate ad imperium-dimissi formulae, cum magis quam 1,200 employees in IX urbes, XV Asset Facilities et VI GMP Servientes Customers in Circiter CLXII. Ashland est vestibulum facilities in Beijing, Tianjin, Shanghai, Nanjing, Changzhou, Kunshan et Jiangmen, et in invested in tres technology investigationis centra in Shanghai et Nanjing.

Secundum website de Sina Cellulose Aether Aether, in MMXVII, in domesticis output de Cellulose aether erat 373,000 tons et Sales volumine erat 360,000 tons. In MMXVII, in ipsa Sales volumine Ionic CMC erat 234,000 tons, usque 18.61% anno in anno, et quod non-Ionic CMC erat 126,000 tons, usque 8.2% anno in anno. Non-Ionic Products praeter HPMC (Aedificium Materials), HPMC (pharmaceutical), HPMC (cibum), HEC, HPC, Mc, Hemc et sic de Bucking et flecte et augendae et sales. Domesticis Cellulose aether crevit cursim plus quam decem annis, output facta est in mundum primo, sed maxime ex products de Cellulose aether conatibus sunt maxime applicantur ad humilis-finem industria, ad additum valorem non altum.

Various cellulose ether enterprise at home and abroad, mostly in the critical period of transformation and upgrading, should continue to strengthen product development, enrich the varieties of products, make full use of the world's largest market, and intensify efforts to develop the foreign market, make the enterprise to complete the transformation and upgrading as soon as possible, into the high-end in the field of industry, realize the benign and green development.